Endocrine Abstracts

Introduction: Acromegaly and Waldenstrom’s macroglobulinaemia are two rare diseases (about 3–4 and 10 cases/million per year respectively), the association between them is even more infrequent, one case being reported in the available literature.Case report: We present the case of a 74-years-old female (I.I.) suffering with both diseases. In 1997 acromegaly diagnosed by dysmorphic syndrome, than in 2004 hormonal/imagistical investigations (GH a...

Introduction: The association of multiple myeloma (MM) with primary hyperparathyroidism (pHPT) is very infrequent. In addition pHPT may be overlooked or later diagnosed, because on the one hand certain clinical and laboratory characteristics of MM, such as hypercalcaemia, asthenia, osteoporosis and impaired renal function overlap with the elements of pHPT, on the other hand modern pHPT include non-classical (e.g. normocalcemic or mild clinical) forms. We present the case of a ...

Objective: To evaluate the effect of selenium on autoimmune thyroid diseases through ATPO-titers.Material and methods: Selenium (0.1–0.2 mg/day) was associated to basic treatment of thyroid dysfunctions in 21 female patients with high ATPO-levels (normal<34 U/ml). We followed the thyroid function and ATPO-values usually after 2–6 months of selenium administration.Results: Ten hypo-thyroid patients had Hashimoto’s...

Objective: To study the efficacy of lithium and perchlorate in special cases of hyperthyroidism: thioamide-resistant or iodine-induced thyroxicosis/thyrotoxic pre-crisis, hematological adverse effects of methimazole, leukopenia of other causes.Material and methods: Twenty-seven hyperthyroid patients received lithium carbonate and/or potassium perchlorate, majority after methimazole-therapy (associated with folic acid in leukopenia). We followed the clini...